1 2007 Vol: 3(5):256-257. DOI: 10.1038/ncprheum0475

Do elevated red blood cell methotrexate polyglutamate levels predict methotrexate efficacy?

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References
  1. Dervieux T et al. (2004) Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis. Arthritis Rheum 50: 2766-2774 , .
    • . . . Dervieux and colleagues have published several articles on potential biomarkers related to response to methotrexate;1, 2, 3 in this study, they present a new series of biomarkers in methotrexate-naive patients . . .
  2. Weisman MH et al. (2006) Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis. Arthritis Rheum 54: 607-612 , .
    • . . . Dervieux and colleagues have published several articles on potential biomarkers related to response to methotrexate;1, 2, 3 in this study, they present a new series of biomarkers in methotrexate-naive patients . . .
  3. Dervieux T et al. (2005) Pharmacogenetic and metabolite measurements are associated with clinical status in patients with rheumatoid arthritis treated with methotrexate: results of a multicentred cross sectional observational study. Ann Rheum Dis 64: 1180-1185 , .
    • . . . Dervieux and colleagues have published several articles on potential biomarkers related to response to methotrexate;1, 2, 3 in this study, they present a new series of biomarkers in methotrexate-naive patients . . .